Ah, George. We know it's not going to work out with Callie. Not going to happen. From one of the greatest shows ever, Seinfeld:
Jason Alexander: "I might... tell her that I love her."
Seinfeld: "Well... that's a big move, Georgie-boy. Are you confident in the 'I love you' return?"
Alexander: "Fifty-fifty."
Seinfeld: "Cuz if you don't get that return... that's a pretty big matzo ball hanging out there."
Since Callie now has the Matzah Ball dangling she knows it's over with George even though he let her down extra nicely. George is still going to be in love with Meredith and I think there's going to be an excellent chance that they hook up again. Meredith is a lonely, cold-hearted *** and George just wants to be with her. It's an accident just waiting to (re-)happen. Does George still have the herpes he got from that nurse that got them from Alex? Is herpes not that bad? They didn't really make a big deal about it but if I had herpes I'd be totally freaking out. I guess they're doctors though. Oh yeah, it's only TV.
==Update==
Ok ok, it's not herpes. It's syphilis treponema. The comments have won. I cannot defeat you.